ZAINA
MIRZA

Biomedical Engineer·Researcher·Applied AI

Building biomedical systems, research workflows, and AI tools that solve real clinical problems.

1st Place EnGenius Award

Recognised for an independent DFU healing prognosis project with real clinical impact potential.

I developed a diabetic foot ulcer healing prognosis model using routinely collected clinical data to support the prediction of healing outcomes. I am incredibly grateful that the hard work, purpose, and potential real-world impact of this research were recognised.

This award is especially meaningful to me because the project was not only academically challenging, but personally challenging too. There were many moments where I doubted myself and questioned whether I was capable of doing research at this level. To have completed this work independently and receive first place among group projects makes this recognition even more special.

Zaina Mirza receiving the EnGenius Award

Receiving the award

EnGenius Award certificate

Certificate

1st PlaceEnGenius Award
AUC 0.758DFU Prognosis
93.5%EMG System Accuracy

Video CV

A one-minute introduction to my background, projects, and interest in biomedical engineering.

1 min

Projects

ROC-AUC by Model

LR
RF
XGB
KNN
Best:KNN 0.758
Clinical MLHonours Capstone
01

Diabetic Foot Ulcer Healing Prognosis

Developed a 4-module machine learning pipeline to predict 12-week healing outcomes in diabetic foot ulcers using routine clinical variables. Applied nested cross-validation, MICE imputation, probability calibration, and threshold optimisation across Logistic Regression, KNN, Random Forest, and XGBoost models.

Pythonscikit-learnNested CVMICE ImputationCalibrationXGBoost

AUC 0.758 · 87 cases · 4-module pipeline

Thermal pipeline
RGBThermalRegistered
Medical Imaging / AI
02

Thermal Image Registration Pipeline

Built an end-to-end pipeline to register RGB images to thermal images and transfer ulcer segmentation masks into thermal space for diabetic foot ulcer assessment. Integrated Meta's SAM2 for wound segmentation, CLAHE for local contrast enhancement, and affine transformation for precise alignment.

PythonOpenCVSAM2 (Meta)PyTorchCLAHEAffine Registration

407 image pairs · SAM2 segmentation · Production-grade

EMG Signal

C4
E4
G4
B4
D5

93.5% accuracy

Signal Processing / ML
03

EMG Gesture Music Therapy

Designed a complete biomedical signal processing system that translates forearm EMG into musical notes for Parkinson's disease rehabilitation. Applied bandpass and notch DSP filtering, wavelet feature extraction, and SVM classification on 24-channel high-density EMG data, mapping gestures to MIDI notes with real-time audio feedback.

PythonSVMLDA24-ch EMGDSPWavelet FeaturesAudio Synthesis

93.5% accuracy · Forearm gesture to MIDI · Parkinson's rehab

CNN Accuracy

98%
CNN
XGB
RF
Medical Imaging / ML
04

Pneumonia Diagnostic Imaging

Built and benchmarked ML pipelines for automated pneumonia classification from chest X-rays. Evaluated Random Forest, XGBoost, and CNN architectures; the CNN achieved near-perfect accuracy, validating deep learning's superiority for medical image classification tasks.

PythonTensorFlowCNNRandom ForestXGBoost

0.98 CNN accuracy · N > 500 chest X-rays

Knee Valgus Angle

0°10°20°30°60°90°60°30°
Naturalpeak 18°
Correctedpeak

N=30 · Rokoko Smartsuit Pro II

Motion Capture
05

Lunge Biomechanics Study

Led a study using the Rokoko Smartsuit Pro II to objectively quantify knee kinematics during lunge exercise in N = 30 participants. Compared natural vs. corrected lunge technique, measuring knee adduction/abduction angles, joint alignment, and trunk inclination to identify ACL injury risk factors undetectable by visual observation.

Rokoko Smartsuit Pro IIJoint Angle AnalysisKinematicsBiomechanics

N=30 participants · Objective vs visual · ACL risk analysis

CAD Schematic

60mm60mm

CATIA 3DX · FEA-optimised · 3D printed

Medical Device Design
06

Assistive Device for Quadriparesis

Designed a parametric assistive device for quadriparesis patients using CATIA 3DEXPERIENCE. Performed Finite Element Analysis to optimise structural integrity, minimise weight, and select materials. Iteratively refined using simulated user feedback and produced manufacturing documentation.

CATIA 3DEXPERIENCESolidWorksFEA3D Printing

FEA-optimised · Parametric design · User-centred

Writing Polish
Web App
07

Writing Polish

Browser-based writing assistant with real-time grammar checking, tone refinement, and dialect options (Australian, American, British, Canadian English). Professional, Concise, and Academic tone modes with inline click-to-apply suggestions.

HTML5CSSJavaScriptHarper

Real-time grammar · 3 tone modes · 4 dialects

Assignment Tracker
Web App
08

Assignment Tracker

Semester planning and grade management tool with teaching-week grouping, colour-coded assignments by weight, smart start-date recommendations, and an interactive grade studio, all stored locally, no cloud required.

HTML5CSSJavaScript

Semester planner · Grade studio · Fully local

ROC-AUC by Model

LR
RF
XGB
KNN
Best:KNN 0.758
Clinical MLHonours Capstone
01

Diabetic Foot Ulcer Healing Prognosis

Developed a 4-module machine learning pipeline to predict 12-week healing outcomes in diabetic foot ulcers using routine clinical variables. Applied nested cross-validation, MICE imputation, probability calibration, and threshold optimisation across Logistic Regression, KNN, Random Forest, and XGBoost models.

Pythonscikit-learnNested CVMICE ImputationCalibrationXGBoost

AUC 0.758 · 87 cases · 4-module pipeline

Thermal pipeline
RGBThermalRegistered
Medical Imaging / AI
02

Thermal Image Registration Pipeline

Built an end-to-end pipeline to register RGB images to thermal images and transfer ulcer segmentation masks into thermal space for diabetic foot ulcer assessment. Integrated Meta's SAM2 for wound segmentation, CLAHE for local contrast enhancement, and affine transformation for precise alignment.

PythonOpenCVSAM2 (Meta)PyTorchCLAHEAffine Registration

407 image pairs · SAM2 segmentation · Production-grade

EMG Signal

C4
E4
G4
B4
D5

93.5% accuracy

Signal Processing / ML
03

EMG Gesture Music Therapy

Designed a complete biomedical signal processing system that translates forearm EMG into musical notes for Parkinson's disease rehabilitation. Applied bandpass and notch DSP filtering, wavelet feature extraction, and SVM classification on 24-channel high-density EMG data, mapping gestures to MIDI notes with real-time audio feedback.

PythonSVMLDA24-ch EMGDSPWavelet FeaturesAudio Synthesis

93.5% accuracy · Forearm gesture to MIDI · Parkinson's rehab

CNN Accuracy

98%
CNN
XGB
RF
Medical Imaging / ML
04

Pneumonia Diagnostic Imaging

Built and benchmarked ML pipelines for automated pneumonia classification from chest X-rays. Evaluated Random Forest, XGBoost, and CNN architectures; the CNN achieved near-perfect accuracy, validating deep learning's superiority for medical image classification tasks.

PythonTensorFlowCNNRandom ForestXGBoost

0.98 CNN accuracy · N > 500 chest X-rays

Knee Valgus Angle

0°10°20°30°60°90°60°30°
Naturalpeak 18°
Correctedpeak

N=30 · Rokoko Smartsuit Pro II

Motion Capture
05

Lunge Biomechanics Study

Led a study using the Rokoko Smartsuit Pro II to objectively quantify knee kinematics during lunge exercise in N = 30 participants. Compared natural vs. corrected lunge technique, measuring knee adduction/abduction angles, joint alignment, and trunk inclination to identify ACL injury risk factors undetectable by visual observation.

Rokoko Smartsuit Pro IIJoint Angle AnalysisKinematicsBiomechanics

N=30 participants · Objective vs visual · ACL risk analysis

CAD Schematic

60mm60mm

CATIA 3DX · FEA-optimised · 3D printed

Medical Device Design
06

Assistive Device for Quadriparesis

Designed a parametric assistive device for quadriparesis patients using CATIA 3DEXPERIENCE. Performed Finite Element Analysis to optimise structural integrity, minimise weight, and select materials. Iteratively refined using simulated user feedback and produced manufacturing documentation.

CATIA 3DEXPERIENCESolidWorksFEA3D Printing

FEA-optimised · Parametric design · User-centred

Writing Polish
Web App
07

Writing Polish

Browser-based writing assistant with real-time grammar checking, tone refinement, and dialect options (Australian, American, British, Canadian English). Professional, Concise, and Academic tone modes with inline click-to-apply suggestions.

HTML5CSSJavaScriptHarper

Real-time grammar · 3 tone modes · 4 dialects

Assignment Tracker
Web App
08

Assignment Tracker

Semester planning and grade management tool with teaching-week grouping, colour-coded assignments by weight, smart start-date recommendations, and an interactive grade studio, all stored locally, no cloud required.

HTML5CSSJavaScript

Semester planner · Grade studio · Fully local

Experience

Bachelor of Engineering (Biomedical) (Honours)

RMIT University

Expected July 2026

WAM 79

International Baccalaureate (IB)

International School of London, Qatar

Secondary School · Graduated 2021

ATAR equivalent 95

ResearchThermal Imaging Pipeline

Research Intern

RMIT University

Nov 2025 – Mar 2026

Melbourne, VIC

  • Built an RGB-thermal registration and wound-segmentation workflow for diabetic foot ulcer imaging, covering preprocessing, alignment, and mask transfer steps for clinician-facing research.
  • Diagnosed reliability issues across thermal imaging and clinical data handoff workflows, improving traceability of outputs for internal review and downstream modelling.
  • Prepared technical reporting, figures, and manuscript material with collaborators, contributing to a first-authored IEEE EMBC 2026 submission.
ResearchPrognosis Modelling

Honours Capstone: AI Prognosis for DFU Healing

RMIT University

Aug 2025 – Present

Melbourne, VIC

  • Built and validated a prognosis workflow for 87 diabetic foot ulcer cases, applying preprocessing, leakage control, structured feature handling, and repeated nested validation.
  • Benchmarked Logistic Regression, Random Forest, XGBoost, and KNN models; best configuration achieved AUC 0.758 and Brier 0.208.
  • Produced honours reporting and thesis material, with progress report scored 90/100.
IndustryOperations & Growth

Operations & Administrative Assistant

Moving Better

Mar 2024 – Jun 2025

Melbourne, VIC

  • Developed and maintained performance dashboards to support operational decisions across client acquisition and service delivery.
  • Supported the launch of a new website and conversion flow, contributing to a 35% increase in customer leads.
  • Coordinated administrative processes, reporting, and client communications across a fast-moving health and wellness business.
  • Planned and executed marketing initiatives to improve reach, engagement, and follow-up.
IndustryTechnical Support

Seasonal Specialist

Apple

Aug 2023 – Feb 2024

Sydney, NSW

  • Delivered high-volume technical support across hardware, software, setup, and service triage, contributing to a 20% increase in customer satisfaction.
  • Built fluency with integrated Apple ecosystem diagnostics and troubleshooting workflows across devices and services.
  • Translated technical issues into clear next steps for customers in a fast-paced retail environment.
OtherCommunity Engagement

Student Ambassador

Scape

Jul 2023 – Feb 2024

Sydney, NSW

  • Coordinated and delivered 10+ community initiatives, including cultural events, exam support, and resident engagement programs, increasing participation by 20%.
  • Implemented feedback-led improvements that contributed to a 12% increase in resident satisfaction scores.
  • Provided day-to-day peer support and onboarding guidance for 150+ students living in residence.

Skills

ML/Data

8 skills
PythonNumPyPyTorchsignal processingEMG analysismachine learningdeep learningdebugging

Signal Processing

5 skills
SVMLDADSP (bandpass/notch)wavelet transforms24-ch EMG

Computer Vision

5 skills
OpenCVSAM2PyTorchCLAHEaffine registration

CAD & Simulation

4 skills
CATIASolidWorksFEA3D printing (FDM/SLA)

Lab

4 skills
Arduino (C/C++)ELISAmicroscopyagarose hydrogel

Web

3 skills
HTML5CSSJavaScript

Tools

3 skills
MATLABGitJupyter

Research

First AuthorManuscript submittedIEEE EMBS International Conference (EMBC) 2026

Healing Prognosis of Diabetic Foot Ulcers Using Routine Clinical Variables

Mirza Z., Sari N.N., Ogrin R., Hanna S., Waller K., Polus B., Ekinci E., Kumar D.K.

RMIT University · Bolton Clarke Research Institute · University of Melbourne · Austin & St Vincent's Hospitals

Dataset

N = 51 de-identified DFU patients

Methods

Logistic Regression, Random Forest, XGBoost, KNN / 5-fold stratified CV

Key Result

ROC-AUC 0.655 · PR-AUC 0.791 · Brier 0.222

Demonstrated that small, low-cost clinical datasets with interpretable models can yield clinically meaningful prognosis without expensive imaging or large-scale data collection.

View Manuscript

Contact

Open to graduate roles, research positions, and internships in healthcare technology, biomedical engineering, and machine learning for clinical applications.

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© 2026 Zaina Mirza